Siena was outscored 9-2 in the second half, allowing No. 4 Johns Hopkins to pull away for the eventual 15-6 victory in the season opener. Sophomore Conor Prunty touched net four times, while senior Matt Sharp had a career-high 20 saves in the loss.
Siena (0-1) got on the board first, nearly three minutes into the game when Prunty tallied an unassisted goal, it would be the last time the Saints scored in the first quarter.
No. 4 Johns Hopkins (1-0) would then score five unanswered goals, with five different players, to conclude the quarter.
Siena would net the first two goals of the second, including scores from Nate Barry, and Prunty's second goal to limit the deficit to 5-3.
The Blue Jays answered back when John Ranagan tallied his second goal of the contest, midway through the second quarter.
The Saints would end the half with another tally from Prunty to complete the hat trick and went into the locker room trailing 6-4.
Johns Hopkins would then score four goals in a span of three minutes, the beginning of a 9-2 run to complete the scoring.
Starting in his first career game, Sharp recorded 20 saves. It was the second year in a row a Saints goalie tallied 20 saves in the season opener.
For the game, Johns Hopkins outshot Siena 58-26. The 58 attempts was the most for the seven-time NCAA champions since 2004. The Blue Jays also collected more groundballs than the Saints (39-17), won more face-offs (16-7), and had less turnovers (15-12).
Senior Danny Martinsen was limited to three shots, and failed to record a point in the contest, ending his 33-game point streak.
The Saints will return home Saturday when they take on Hobart.